Antiretroviral combination therapy (cART) has increased the service life of People live on HIV (PLWH). As long-term survival rises, PLWH may have metabolic and cardiovascular disorders such as diabetes, cardiovascular disease, obesity, metabolic syndrome, and dyslipidaemia more often than others. Moreover, although persons receiving cART have fewer AIDS-related diseases than cART-na€Ä±ve PLWH overall, exposure to cART, particularly protease inhibitors (PIs), may increase the risk of cardiometabolic disease. One research found no substantial difference in the incidence of diabetes between WLWH and HIV-negative women among women living with HIV (WLWH), while another recorded a lower prevalence of hypertension but an elevated risk of cardiovascular disease in WLWH relative to HIV-negative people. Blood mitochondrial DNA content (mtDNA: nuclear DNA ratio) and leukocyte telomere length (LTL) are cellular aging markers and have been correlated with many of the above-mentioned conditions. Women living with HIV show signs of accelerated aging and experience menopause at a younger age compared to HIV-negative women. As data comparing age-related comorbidities and cellular markers of aging among WLWH are scarce, we investigated the prevalence and predictors of cardiometabolic disease among WLWH and HIV-negative women involved in Children and Adolescents: Antiretrovirals and Markers of Children and Women Analysis of population Aging (CARMA). Researchers carried out a retrospective, cross-sectional study of data from 289 non-pregnant women, 156 of whom had HIV and 133 of whom did not, aged 12 to 69. In order to determine Framingham risk score (FRS) and prevalence of hypertension , diabetes, metabolic syndrome and dyslipidemia, the investigators used self-report, anthropometrics, chart review and laboratory data. Women in the HIV-positive group were less likely to be menopausal or use alcohol, and more often had an infection with hepatitis C virus or a current or past history of smoking. Only lower mitochondrial DNA content was associated with metabolic syndrome in terms of the associations between cardiometabolic abnormalities and cellular ageing markers. This review tells about the future scope of the new invention towards the field of HIV /AIDS and their medicinal treatment. People who are interested can send their article towards our journal for publication through this link https://www.scholarscentral.org/submissions/hiv-aids-research.html